Predictors of Intraspinal Pressure and Optimal Cord Perfusion Pressure After Traumatic Spinal Cord Injury.

ABSTRACT:

Background/objectives

We recently developed techniques to monitor intraspinal pressure (ISP) and spinal cord perfusion pressure (SCPP) from the injury site to compute the optimum SCPP (SCPP_opt) in patients with acute traumatic spinal cord injury (TSCI). We hypothesized that ISP and SCPP_opt can be predicted using clinical factors instead of ISP monitoring.

Methods

Sixty-four TSCI patients, grades A-C (American spinal injuries association Impairment Scale, AIS), were analyzed. For 24 h after surgery, we monitored ISP and SCPP and computed SCPP_opt (SCPP that optimizes pressure reactivity). We studied how well 28 factors correlate with mean ISP or SCPP_opt including 7 patient-related, 3 injury-related, 6 management-related, and 12 preop

SUBMITTER: Hogg FRA 

PROVIDER: S-EPMC6420421 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature