Pulmonary infections prime the development of subsequent ICU-acquired pneumonia in septic shock.

ABSTRACT: PURPOSE:To investigate the determinants and the prognosis of intensive care unit (ICU)-acquired pneumonia in patients with septic shock. METHODS:This single-center retrospective study was conducted in a medical ICU in a tertiary care center from January 2008 to December 2016. All consecutive patients diagnosed for septic shock within the first 48 h of ICU admission were included. Patients were classified in three groups: no ICU-acquired infections (no ICU-AI), ICU-acquired pneumonia and non-pulmonary ICU-AI. The determinants of ICU-acquired pneumonia and death were investigated by multivariate competitive risk analysis. RESULTS:A total of 1021 patients were admitted for septic shock, and 797 patients were alive in the ICU after 48 h of management. The incidence of a first episode of ICU-AI

SUBMITTER: Llitjos JF 

PROVIDER: S-EPMC6420540 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature