Microvascular characteristics of lower-grade diffuse gliomas: investigating vessel size imaging for differentiating grades and subtypes.

ABSTRACT:

Objectives

Vessel size imaging (VSI) could reveal average microvessel diameter. The aim was to investigate microvascular characteristics and the efficacy of VSI in lower-grade glioma (LGG) grading and subtype differentiation based on 2016 classification of central nervous system tumours.

Methods

Fifty-seven LGG (grade II/III, 36/21) patients who received VSI examination before surgery were retrospectively analysed. The average (R_mean) and maximum (R_max) vessel size indexes were obtained. The long (VD_max) and short (VD_min) vascular diameter, microvascular area (MVA) and density (MVD) were obtained using paraffin specimens. The patients were divided into grades II and III, and histological and molecular subtypes. The differences amon

SUBMITTER: Guo H 

PROVIDER: S-EPMC6420610 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature