Women's preferences for cancer risk management strategies in Lynch syndrome.

ABSTRACT:

Objective

We assessed preferences for cancer risk management strategies for Lynch syndrome (LS) in LS-affected women.

Methods

Women with LS aged ≥25 years evaluated 9 cancer risk management strategies using a visual analog scale (VAS) and modified standard gamble (SG). For the VAS, women ranked each strategy ranging from 0 (least preferred) to 100 (most preferred). VAS scores were calculated by dividing the corresponding number by 100. Scores closer to 1.0 reflected more favorable strategies. For the SG, participants were asked to specify their expected threshold of lifetime risk of endometrial or colorectal cancer, ranging from 0 to 100%, at which they would consider undertaking each strategy. Strategies included chemoprevention, cancer screening, and preventive surgery. Ca

SUBMITTER: Sun CC 

PROVIDER: S-EPMC6422049 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature