Arterial flow patterns in healthy transitioning near-term neonates.

ABSTRACT:

Objective

Significant haemodynamic changes occur at delivery impacting organ blood flow distribution. We aimed to characterise Doppler indices patterns over time in three different organs (brain, gut and kidney) and test them as measures of vascular resistance.

Design

Observational cohort study. Serial Doppler interrogations of the anterior cerebral, superior mesenteric and renal arteries within 2 hours, 2-6, and 24 hours of life, in combination with central haemodynamic data.

Patients

Healthy, near-term (>36 weeks of gestation) neonates.

Outcome measures

Pulsatility (PI) and Resistance Indices (RI) patterns and organ-specific conductances, detailed echocardiographic haemodynamic measures.

Results

Twenty-one babies were studied. Doppler morphology and ad

SUBMITTER: Stritzke A 

PROVIDER: S-EPMC6422249 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature