Barriers to achieving asthma control in adults: evidence for the role of tiotropium in current management strategies.

ABSTRACT: Despite the availability of a range of treatment options and management guidelines, a high proportion of adults with asthma remain uncontrolled. The challenge of managing uncontrolled asthma includes providing efficacious treatment while limiting side effects, recognizing situations when a change in asthma therapy is required, and considering patient preferences and satisfaction. In line with the Global Initiative for Asthma report, asthma management is based on a backbone of inhaled corticosteroid (ICS) therapy and use of add-on therapies to achieve disease control. This review considers whether add-on options could be better utilized in clinical practice. A number of long-acting muscarinic antagonists are in development, but tiotropium is the most widely studied for use in asthma. Eviden

SUBMITTER: Jenkins C 

PROVIDER: S-EPMC6422417 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature