Effects of seafood consumption and toenail mercury and selenium levels on cognitive function among American adults: 25 y of follow up.

ABSTRACT:

Objectives

The aim of this study was to examine the longitudinal association between seafood and intake of long-chain ω-3 polyunsaturated fatty acids (LCω-3 PUFA) and cognitive function and to explore the possible effect modifications owing to mercury (Hg) and selenium (Se) levels.

Methods

Participants (N = 3231) from the CARDIA (Coronary Artery Risk Development in Young Adults) study underwent baseline examination and were reexamined in eight follow-up visits. Diet was assessed at baseline and in exam years 7 and 20. Toenail Hg and Se were measured at exam year 2. Cognitive function was measured at exam year 25 using three tests: Rey Auditory Verbal Learning Test (RAVLT), Digit Symbol Substitution Test (DSST), and the Stroop test. The general linear regression model was use

SUBMITTER: Mao X 

PROVIDER: S-EPMC6422693 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature