Synthesis of the aglycon of scorzodihydrostilbenes B and D.

ABSTRACT: Benzyl- and methyl-protected 2,4-dihydroxyacetophenones are added under ruthenium catalysis to 4-methoxy- and 3,4-dimethoxystyrene in a completely regioselective manner. Thus, oxygenated dihydrostilbenes are obtained that feature the skeleton of scorzodihydrostilbenes - antioxidative agents that were recently isolated from Scorzonera radiata. Selective deprotection liberates the corresponding phenols, among them the aglycon of scorzodihydrostilbenes B and D.

SUBMITTER: Weimann K 

PROVIDER: S-EPMC6423597 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature