Multicentre pilot randomised clinical trial of early in-bed cycle ergometry with ventilated patients.

ABSTRACT:

Introduction

Acute rehabilitation in critically ill patients can improve post-intensive care unit (post-ICU) physical function. In-bed cycling early in a patient's ICU stay is a promising intervention. The objective of this study was to determine the feasibility of recruitment, intervention delivery and retention in a multi centre randomised clinical trial (RCT) of early in-bed cycling with mechanically ventilated (MV) patients.

Methods

We conducted a pilot RCT conducted in seven Canadian medical-surgical ICUs. We enrolled adults who could ambulate independently before ICU admission, within the first 4 days of invasive MV and first 7 days of ICU admission. Following informed consent, patients underwent concealed randomisation to either 30 min/day of in-bed cycling and routin

SUBMITTER: Kho ME 

PROVIDER: S-EPMC6424272 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature