Management of atrial fibrillation for older people with frailty: a systematic review and meta-analysis.

ABSTRACT:

Background

despite a large and growing population of older people with frailty and atrial fibrillation (AF), there is a lack of guidance on optimal AF management in this high-risk group.

Objective

to synthesise the existing evidence base on the association between frailty, AF and clinical outcomes.

Methods

a systematic review of studies examining the association between validated measures of frailty, AF and clinical outcomes, and meta-analysis of the association between frailty and oral anticoagulation (OAC) prescription.

Results

twenty studies (30,883 patients) were included, all observational. Fifteen were in hospital, four in the community, one in nursing care. Risk of bias was low-to-moderate. AF prevalence was 3%-38%. In people with AF, frailty was associa

SUBMITTER: Wilkinson C 

PROVIDER: S-EPMC6424377 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature