Pyramidal system involvement in progressive supranuclear palsy - a clinicopathological correlation.

ABSTRACT:

Background

We aimed to produce a detailed neuropathological analysis of pyramidal motor system pathology and provide its clinical pathological correlation in cases with definite progressive supranuclear palsy (PSP).

Methods

Pyramidal motor system pathologies were analyzed in 18 cases with neuropathologically confirmed PSP. Based on a retrospective clinical analysis, cases were subtyped according to Movement Disorder Society criteria for clinical diagnosis of PSP as probable, possible or suggestive of PSP with Richardson's syndrome (n = 10), PSP with predominant corticobasal syndrome (n = 3), PSP with predominant parkinsonism (n = 3), PSP with predominant speech/language disorder (n = 1), and PSP with progressive gait freezing (n = 1). Clinical manifestations of motor neuron

SUBMITTER: Stejskalova Z 

PROVIDER: S-EPMC6425568 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature