Is there a sex difference in postoperative prognosis of hepatocellular carcinoma?

ABSTRACT:

Background

Although men carry a higher risk of hepatocellular carcinoma (HCC) than women, it is still controversial whether men also have a poorer postoperative prognosis. A retrospective study was conducted to evaluate the postoperative prognostic predictors of HCC focusing on sex differences.

Methods

We enrolled 516 consecutive adult patients with HCC (118 women, 398 men), who received surgical resection between January 2000 and December 2007, and were followed-up for >10 years. Clinical and laboratory data together with postoperative outcomes were reviewed.

Results

At baseline, female patients had a higher anti-hepatitis C virus antibody prevalence (P = 0.002); lower hepatitis B virus surface antigen prevalence (P = 0.006); less microvascular invasion (P = 0.019);

SUBMITTER: Lai MW 

PROVIDER: S-EPMC6425676 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature