Prenatal and infant exposure to ambient pesticides and autism spectrum disorder in children: population based case-control study.

ABSTRACT:

Objective

To examine associations between early developmental exposure to ambient pesticides and autism spectrum disorder.

Design

Population based case-control study.

Setting

California's main agricultural region, Central Valley, using 1998-2010 birth data from the Office of Vital Statistics.

Population

2961 individuals with a diagnosis of autism spectrum disorder based on the Diagnostic and Statistical Manual of Mental Disorders, fourth edition, revised (up to 31 December 2013), including 445 with intellectual disability comorbidity, were identified through records maintained at the California Department of Developmental Services and linked to their birth records. Controls derived from birth records were matched to cases 10:1 by sex and birth year.

E

SUBMITTER: von Ehrenstein OS 

PROVIDER: S-EPMC6425996 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature