Effect of Aspirin on Disability-free Survival in the Healthy Elderly.

ABSTRACT:

Background

Information on the use of aspirin to increase healthy independent life span in older persons is limited. Whether 5 years of daily low-dose aspirin therapy would extend disability-free life in healthy seniors is unclear.

Methods

From 2010 through 2014, we enrolled community-dwelling persons in Australia and the United States who were 70 years of age or older (or ≥65 years of age among blacks and Hispanics in the United States) and did not have cardiovascular disease, dementia, or physical disability. Participants were randomly assigned to receive 100 mg per day of enteric-coated aspirin or placebo orally. The primary end point was a composite of death, dementia, or persistent physical disability. Secondary end points reported in this article included the individual

SUBMITTER: McNeil JJ 

PROVIDER: S-EPMC6426126 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature