The role of specialized hospital units in infection and mortality risk reduction among patients with hematological cancers.

ABSTRACT:

Motivation

Patients with hematological malignancies are susceptible to life-threatening infections after chemotherapy. The current study aimed to evaluate whether management of such patients in dedicated inpatient and emergency wards could provide superior infection prevention and outcome.

Methods

We have developed an approach allowing to retrieve infection-related information from unstructured electronic medical records of a tertiary center. Data on 2,330 adults receiving 13,529 chemotherapy treatments for hematological malignancies were identified and assessed. Infection and mortality hazard rates were calculated with multivariate models. Patients were randomly divided into 80:20 training and validation cohorts. To develop patient-tailored risk-prediction models, several m

SUBMITTER: Carmen R 

PROVIDER: S-EPMC6426175 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature