Development and Validation of Nomograms for Malignancy Prediction in Soft Tissue Tumors Using Magnetic Resonance Imaging Measurements.

ABSTRACT: The objective of this study was to develop, validate, and compare nomograms for malignancy prediction in soft tissue tumors (STTs) using conventional and diffusion-weighted magnetic resonance imaging (MRI) measurements. Between May 2011 and December 2016, 239 MRI examinations from 236 patients with pathologically proven STTs were included retrospectively and assigned randomly to training (n = 100) and validation (n = 139) cohorts. MRI of each lesion was reviewed to assess conventional and diffusion-weighted imaging (DWI) measurements. Multivariate nomograms based on logistic regression analyses were built using conventional measurements with and without DWI measurements. Predictive accuracy was measured using the concordance index (C-index) and calibration plots. Statistical differences be

SUBMITTER: Lee JH 

PROVIDER: S-EPMC6427044 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature