Measurement of an Analyte Concentration in Test Solution by Using Helmholtz Resonator for Biosensor Applications.

ABSTRACT: In this paper, an indirect method of measuring an analyte concentration in a test solution using the resonant frequency change of a Helmholtz resonator is proposed, using a novel architecture of Helmholtz resonator filled with two kinds of fluids (fixed fluid and test solution). Since the analyte concentration yields changes of density and sound speed of the test solution, the resonant frequency of the proposed Helmholtz resonator is affected by the analyte concentration of the test solution. From this effect, the analyte concentration of the test solution can be measured by the spectrum of acoustic resonance of the Helmholtz resonator. The experiment was done using a 3D-printed Helmholtz resonator system with an acoustic power source and detectors, which is consistent with analytical resu

SUBMITTER: Chen Y 

PROVIDER: S-EPMC6427302 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature