Genotypic diversity of Mycobacterium tuberculosis isolates from North-Central Indian population.

ABSTRACT: BACKGROUND:Different strains of Mycobacterium tuberculosis (MTB) are known to have different epidemiological and clinical characteristics. Some of them are widely distributed and associated with drug resistance, whereas others are locally predominated. Molecular epidemiological investigations have always been beneficial in identifying new strains and studying their transmission dynamics. Sahariya a primitive tribe of North Madhya Pradesh, India, has already been reported to have high prevalence of tuberculosis (TB) than their non-tribal neighbours. However, the information about MTB genotypes prevalent in Sahariya tribe and their non-tribal neighbours is not available. METHODS:A total of 214 clinical isolates representing Sahariya tribe and non-tribes were analyzed by spoligotyping and MIR

SUBMITTER: Prakash R 

PROVIDER: S-EPMC6427501 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature