Relative effects of location relative to the corpus luteum and lactation on the transcriptome of the bovine oviduct epithelium.

ABSTRACT:

Background

Lactation and associated metabolic stresses during the post-partum period have been shown to impair fertility in dairy cows. The oviduct plays key roles in embryo development and the establishment of pregnancy in cattle. The aim of this study was to investigate the effects of lactation and location relative to the corpus luteum (CL) on the transcriptome of the bovine oviduct epithelium.

Results

An original animal model was used. At 60 days post-partum, Holstein lactating (n = 4) and non-lactating (i.e. never milked after calving; n = 5) cows, as well as control nulliparous heifers (n = 5), were slaughtered on Day 3 following induced estrus, and epithelial samples from the oviductal ampulla and isthmus ipsilateral and contralateral to the corpus luteum (CL) were re

SUBMITTER: Locatelli Y 

PROVIDER: S-EPMC6427878 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature