Retrospective investigation of antibodies against chikungunya virus (CHIKV) in serum from febrile patients in Mozambique, 2009-2015: Implications for its prevention and control.

ABSTRACT:

Introduction

Longitudinal data and trends about chikungunya virus (CHIKV) are critical for its control, however in Mozambique very few studies were conducted over 5 decades, between 1957 and 2013. In this study, we retrospectively investigated the occurrence, geographical distribution and trend of anti-CHIKV antibodies between 2009 and 2015 in Mozambique using serum samples from febrile patients.

Methods

A total of 895 serum samples collected from febrile patients for measles and rubella surveillance between 2009 and 2015 in 127 districts of Mozambique were retrospectively tested for IgM and IgG antibodies against CHIKV using a commercially available ELISA.

Results

The median age of patients was 2 years (IQR: 1-5 years) and 44.2% (395/895) of them were female. We foun

SUBMITTER: Antonio VS 

PROVIDER: S-EPMC6428254 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature