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Association of Single Nucleotide Polymorphisms (SNPs) in Genes Encoding for Folate Metabolising Enzymes with Glioma and Meningioma in Indian Population


ABSTRACT: Background: The association of primary brain tumors with Single Nucleotide polymorphisms (SNPs) in genes of

SUBMITTER: Kumawat R 

PROVIDER: S-EPMC6428555 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature

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Association of Single Nucleotide Polymorphisms (SNPs) in Genes Encoding for Folate Metabolising Enzymes with Glioma and Meningioma in Indian Population

Kumawat Rajani R   Gowda Srinivas H SH   Debnath Ekta E   Rashid Safoora S   Niwas Ram R   Gupta Yakhlesh Y   Upadaya Ashish Datta AD   Suri Ashish A   Chandra P Sarat PS   Gupta Deepak K DK   Lakshmy Ramakrishnan R   Sarkar Chitra C   Sinha Subrata S   Chosdol Kunzang K  

Asian Pacific journal of cancer prevention : APJCP 20181225 12


Background: The association of primary brain tumors with Single Nucleotide polymorphisms (SNPs) in genes of folate metabolising enzymes have been reported to vary among different ethnic population. Here, we have studied the association of SNPs of folate metabolizing genes with the primary brain tumors (glioma and meningioma) in North Indian population. Methods: SNPs of genes coding for folate metabolizing enzymes was carried out in 288 study population from North India [Glioma (n=108), Meningiom  ...[more]

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