Genome-Wide Identification and Expression Profiling of Wnt Family Genes in the Silkworm, Bombyx mori.

ABSTRACT: Wnt is a family of conserved glycoproteins that participate in a variety of important biological processes including embryo development, cell proliferation and differentiation, and tissue regeneration. The Wnt family is a metazoan novelty found in all animal phyla. Studies have revealed that the number of Wnt genes varies among species, presumably due to reproduction and loss of genes during evolution. However, a comprehensive inventory of Wnt genes in Lepidoptera is lacking. In this study, we identified the repertoire of Wnt genes in the silkworm and seven other species of Lepidoptera and obtained eight Wnt genes (Wnt1, Wnt5⁻Wnt7, Wnt9⁻Wnt11, and WntA) in each species. Four of these Wnt genes are clustered in two

SUBMITTER: Ding X 

PROVIDER: S-EPMC6429082 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature