Rh(III)-Catalyzed Annulation of Boc-Protected Benzamides with Diazo Compounds: Approach to Isocoumarins.

ABSTRACT: A mild rhodium-catalyzed annulation of Boc-protected benzamides with diazo compounds via C-C/C-O bond formation has been explored. In the presence of [Cp*RhCl₂]₂, AgSbF₆ and Cs₂CO₃, Boc-protected benzamides can be effectively annulated to yield isocoumarins in 0.5⁻2 h.

SUBMITTER: Dong G 

PROVIDER: S-EPMC6429621 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature