Tibial nerve decompression for the prevention of the diabetic foot: a cost-utility analysis using Markov model simulations.

ABSTRACT:

Objective

To determine whether tibial neurolysis performed as a surgical intervention for patients with diabetic neuropathy and superimposed tibial nerve compression in the prevention of the diabetic foot is cost-effective when compared with the current prevention programme.

Design

A baseline analysis was built on a 5-year model to determine the cumulative incidence of foot ulcers and amputations with each strategy. Subsequently, a cost-effectiveness analysis and cohort-level Markov simulations were conducted with a model composed of 20 6-month cycles. A sensitivity analysis was also performed.

Setting

A Markov model was used to simulate the effects of standard prevention compared with tibial neurolysis on the long-term costs associated with foot ulcers and amputation

SUBMITTER: Sarmiento S 

PROVIDER: S-EPMC6429851 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature