Association between perinatal interventional activity and 2-year outcome of Swiss extremely preterm born infants: a population-based cohort study.

ABSTRACT:

Objectives

To investigate if centre-specific levels of perinatal interventional activity were associated with neonatal and neurodevelopmental outcome at 2 years of age in two separately analysed cohorts of infants: cohort A born at 22-25 and cohort B born at 26-27 gestational weeks, respectively.

Design

Geographically defined, retrospective cohort study.

Setting

All nine level III perinatal centres (neonatal intensive care units and affiliated obstetrical services) in Switzerland.

Patients

All live-born infants in Switzerland in 2006-2013 below 28 gestational weeks, excluding infants with major congenital malformation.

Outcome measures

Outcomes at 2 years corrected for prematurity were mortality, survival with any major neonatal morbidity and with severe

SUBMITTER: Adams M 

PROVIDER: S-EPMC6429852 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature