Acute kidney injury and 1-year mortality after colorectal cancer surgery: a population-based cohort study.

ABSTRACT:

Objectives

Acute kidney injury (AKI) is a frequent postoperative complication, but the mortality impact within different postoperative time frames and severities of AKI are poorly understood. We examined the occurrence of postoperative AKI among colorectal cancer (CRC) surgery patients and the impact of AKI on mortality during 1 year after surgery.

Design

Observational cohort study. We defined the exposure, AKI, as a 50% increase in plasma creatinine or initiation of renal replacement therapy within 7 days after surgery or an absolute increase in creatinine of 26 µmol/L within 48 hours.

Setting

Population-based Danish medical databases.

Participants

A total of 6580 patients undergoing CRC surgery in Northern Denmark during 2005-2011 were included from the Danis

SUBMITTER: Slagelse C 

PROVIDER: S-EPMC6429863 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature