PrEP Implementation for Mothers in Antenatal Care (PrIMA): study protocol of a cluster randomised trial.

ABSTRACT:

Introduction

Women in regions with high HIV prevalence are at high risk of HIV acquisition during pregnancy and postpartum, and acute maternal HIV contributes a substantial proportion of infant HIV infections. Pre-exposure prophylaxis (PrEP) could prevent HIV during pregnancy/postpartum; however, identifying women who would most benefit from PrEP in this period is challenging. Women may not perceive risk, may not know partner HIV status and partners may have external partners during this period. PrEP offer in pregnancy could be universal or risk guided.

Methods and analysis

The PrEP Implementation for Mothers in Antenatal Care (PrIMA) study is a cluster randomised trial that aims to determine the best model for PrEP implementation in pregnancy, among women attending public s

SUBMITTER: Dettinger JC 

PROVIDER: S-EPMC6430021 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature