Distribution of toxicity values across different species and modes of action of pesticides from PESTIMEP and PPDB databases.

ABSTRACT: The continuous use of compounds contained in commodities such as processed food, medicines, and pesticides, demands safety measures, in particular, for those in direct contact with humans and the environment. Safety measures have evolved and regulations are now in place around the globe. In the case of pesticides, attempts have been made to use toxicological data to inform of potentially harmful compounds either across species, on different routes of exposure, or entirely new chemicals. The generation of models, based on statistical and molecular modeling studies, allows for such predictions. However, the use of these models is framed by the available data, the experimental errors, the complexity of the measurement, and the available computational algorithms, among other factors. In this w

SUBMITTER: Madariaga-Mazon A 

PROVIDER: S-EPMC6430098 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature