Self-organized mechano-chemical dynamics in amoeboid locomotion of Physarum fragments.

ABSTRACT: The aim of this work is to quantify the spatio-temporal dynamics of flow-driven amoeboid locomotion in small (~100 µm) fragments of the true slime mold Physarum polycephalum. In this model organism, cellular contraction drives intracellular flows, and these flows transport the chemical signals that regulate contraction in the first place. As a consequence of these non-linear interactions, a diversity of migratory behaviors can be observed in migrating Physarum fragments. To study these dynamics, we measure the spatio-temporal distributions of the velocities of the endoplasm and ectoplasm of each migrating fragment, the traction stresses it generates on the substratum, and the concentration of free intracellular calcium. Using these unprecedented experimental data, we classify migrating Phy

SUBMITTER: Zhang S 

PROVIDER: S-EPMC6430145 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature