Impaired ankle-brachial index in antiphospholipid syndrome: Beyond the traditional risk factors.

ABSTRACT:

Introduction

The patients with antiphospholipid syndrome (APS) associate an increased risk of atherosclerosis.

Objective

To determine the predictors of an abnormal ankle-brachial index (ABI), surrogate measure of atherosclerosis, in patients with APS.

Methods

The ABI was measured according to standard recommendations in 106 patients. Traditional cardiovascular risk factors were assessed in all cases. A large spectrum of APS antibodies was determined in 73 patients.

Results

A total of 106 patients diagnosed with APS were included. 28.3% patients included were found to have low ABI. Anti-beta 2-glycoprotein I (aβ2GPI) IgG antibodies [4.00 (1.00-79.00) vs 3.00 (0.00-29.00) U/mL, P = 0.02] and antiprothrombin (aPT) IgM antibodies [4.50 (0.00-82.00) vs 3.00 (0.00-14

SUBMITTER: Caraiola S 

PROVIDER: S-EPMC6430368 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature