Echocardiographic indices and severity of mitral regurgitation in dogs with preclinical degenerative mitral valve disease.

ABSTRACT:

Background

Describing severity of mitral regurgitation (MR) in dogs with degenerative mitral valve disease (DMVD) is challenging.

Hypothesis/objectives

Mitral regurgitant fraction (RF), effective regurgitant orifice area (EROA), and the ratio of mitral regurgitant to aortic flow (Q_MR :Q_Ao ) can be calculated from routine echocardiographic measurements and provide additional information regarding MR severity.

Animals

Fifty-seven dogs with preclinical DMVD including 36 without and 21 with cardiomegaly.

Methods

Prospective observational study. The expected relationships among RF, EROA, and Q_MR :Q_Ao and 1-dimensional measurements including left atrium to aortic root diameter ratio (LA:Ao) and normalized left ventricular i

SUBMITTER: Larouche-Lebel E 

PROVIDER: S-EPMC6430891 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature