Interactive programming paradigm for real-time experimentation with remote living matter.

ABSTRACT: Recent advancements in life-science instrumentation and automation enable entirely new modes of human interaction with microbiological processes and corresponding applications for science and education through biology cloud laboratories. A critical barrier for remote and on-site life-science experimentation (for both experts and nonexperts alike) is the absence of suitable abstractions and interfaces for programming living matter. To this end we conceptualize a programming paradigm that provides stimulus and sensor control functions for real-time manipulation of physical biological matter. Additionally, a simulation mode facilitates higher user throughput, program debugging, and biophysical modeling. To evaluate this paradigm, we implemented a JavaScript-based web toolkit, "Bioty," that su

SUBMITTER: Washington P 

PROVIDER: S-EPMC6431204 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature