Risk Factors for Developing Nonmelanoma Skin Cancer after Lung Transplantation.

ABSTRACT:

Background

Nonmelanoma skin cancer (NSMC) is the most common malignancy after organ transplantation. Lung transplant recipients (LTRs) are particularly prone to develop NMSC as compared to renal or hepatic transplant recipients due to higher dosages of immunosuppression needed. Everolimus, an immunosuppressant used in organ transplant recipients, is thought to inherit a lower risk for NMSC than calcineurin inhibitors, especially in renal transplant recipients. It is currently unknown whether this also applies to LTRs.

Objectives

To determine risk factors for NMSC and precancerous lesions after lung transplantation (LTx) and to characterize the effect of everolimus-based regimens regarding this risk.

Materials and methods

90 LTRs and former participants of the interven

SUBMITTER: Grager N 

PROVIDER: S-EPMC6431522 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature