High-frequency repetitive TMS for suicidal ideation in adolescents with depression.

ABSTRACT:

Background

This exploratory study sought to examine the effect of an acute course of high-frequency repetitive TMS on suicidal ideation in adolescents.

Methods

Data were pooled from 3 prior protocols providing a 30-session course of open-label TMS treatment for adolescents with treatment-resistant depression. All participants (n = 19) were outpatients taking antidepressant medication, with TMS provided as adjunctive treatment. Suicidality was assessed at baseline, after 10 treatments, after 20 treatments, and after 30 treatments. Outcome measures of suicidal ideation included the Columbia Suicide Severity Rating Scale (C-SSRS) "Intensity of Ideation" subscale and Item 13 "Suicidality" on the Children's Depression Rating Scale, Revised (CDRS-R).

Results

The predicted o

SUBMITTER: Croarkin PE 

PROVIDER: S-EPMC6431788 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature