Frequency-specific coupling in fronto-parieto-occipital cortical circuits underlie active tactile discrimination.

ABSTRACT: Processing of tactile sensory information in rodents is critically dependent on the communication between the primary somatosensory cortex (S1) and higher-order integrative cortical areas. Here, we have simultaneously characterized single-unit activity and local field potential (LFP) dynamics in the S1, primary visual cortex (V1), anterior cingulate cortex (ACC), posterior parietal cortex (PPC), while freely moving rats performed an active tactile discrimination task. Simultaneous single unit recordings from all these cortical regions revealed statistically significant neuronal firing rate modulations during all task phases (anticipatory, discrimination, response, and reward). Meanwhile, phase analysis of pairwise LFP recordings revealed the occurrence of long-range synchronization across

SUBMITTER: Kunicki C 

PROVIDER: S-EPMC6434051 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature