Chemical and Bioactivity Evaluation of Eryngium planum and Cnicus benedictus Polyphenolic-Rich Extracts.

ABSTRACT: This study evaluated the biological activities of Eryngium planum and of Cnicus benedictus extracts enriched in polyphenols obtained by nanofiltration. The HPLC-MS analysis showed that E. planum contains mainly flavonoids, especially rutin, while in C. benedictus extracts show the high concentration of the phenolic acids, principally the chlorogenic acid and sinapic acid. Herein, there is the first report of ursolic acid, genistin, and isorhamnetin in E. planum and C. benedictus. C. benedictus polyphenolic-rich extract showed high scavenging activity (IC₅₀=0.0081 mg/mL) comparable to that of standard compound (ascorbic acid) and a higher reducing power (IC₅₀= 0.082 mg/mL), with IC₅₀ having a significantly lower valu

SUBMITTER: Paun G 

PROVIDER: S-EPMC6434295 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature