Cellular and Site-Specific Mitochondrial Characterization of Vital Human Amniotic Membrane.

ABSTRACT: Over a century ago, clinicians started to use the human amniotic membrane for coverage of wounds and burn injuries. To date, literally thousands of different clinical applications exist for this biomaterial almost exclusively in a decellularized or denuded form. Recent reconsiderations for the use of vital human amniotic membrane for clinical applications would take advantage of the versatile cells of embryonic origin including the entirety of their cell organelles. Recently, more and more evidence was found, showing mitochondria to be involved in most fundamental cellular processes, such as differentiation and cell death. In this study, we focused on specific properties of mitochondria of vital human amniotic membrane and characterized bioenergetical parameters of 2 subregions of the huma

SUBMITTER: Banerjee A 

PROVIDER: S-EPMC6434485 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature