Socioeconomic status and early blood concentrations of inflammation-related and neurotrophic proteins among extremely preterm newborns.

ABSTRACT: The main objective of this study was to evaluate the relationship between mother's socioeconomic disadvantage and blood concentrations of inflammation-related proteins among extremely preterm newborns (<28 weeks gestation), a group at heightened risk of cognitive impairment when exposed to systemic inflammation. We measured the concentrations of 27 inflammatory and neurotrophic proteins in blood specimens collected a week apart during the first postnatal month from 857 extremely preterm newborns in the United States. We classified children according to 3 indicators/correlates of socioeconomic disadvantage, mother's eligibility for government-provided medical care insurance (Medicaid), mother's formal education level, and mother's IQ approximated with the Kaufman Brief Intelligence Test- 2.

SUBMITTER: Leviton A 

PROVIDER: S-EPMC6435168 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature