Data-Driven Topological Filtering Based on Orthogonal Minimal Spanning Trees: Application to Multigroup Magnetoencephalography Resting-State Connectivity.

ABSTRACT: In the present study, a novel data-driven topological filtering technique is introduced to derive the backbone of functional brain networks relying on orthogonal minimal spanning trees (OMSTs). The method aims to identify the essential functional connections to ensure optimal information flow via the objective criterion of global efficiency minus the cost of surviving connections. The OMST technique was applied to multichannel, resting-state neuromagnetic recordings from four groups of participants: healthy adults (n = 50), adults who have suffered mild traumatic brain injury (n = 30), typically developing children (n = 27), and reading-disabled children (n = 25). Weighted interactions between network nodes (sensors) were computed using an integrated approach of dominant intrinsic coupling

SUBMITTER: Dimitriadis SI 

PROVIDER: S-EPMC6435350 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature