Chemosensory Event-Related Potentials in Response to Nasal Propylene Glycol Stimulation.

ABSTRACT: Propylene glycol, also denoted as 1.2 propanediol (C₃H₈O₂), often serves as a solvent for dilution of olfactory stimuli. It is supposed to serve as a neutral substance and has been used in many behavioral and electrophysiological studies to dilute pure olfactory stimuli. However, the effect of propylene glycol on perception and on neuronal responses has hitherto never been studied. In this study we tested by means of a threshold test, whether a nasal propylene glycol stimulation is recognizable by humans. Participants were able to recognize propylene glycol at a threshold of 42% concentration and reported a slight cooling effect. In addition to the threshold test, we recorded electroencephalography (EEG) during nasal propylene glycol stimulation to study th

SUBMITTER: Sirous M 

PROVIDER: S-EPMC6435593 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature