An Essential Role of the Intraparietal Sulcus in Response Inhibition Predicted by Parcellation-Based Network.

ABSTRACT: The posterior parietal cortex (PPC) features close anatomical and functional relationships with the prefrontal cortex. However, the necessity of the PPC in executive functions has been questioned. The present study used the stop-signal task to examine response inhibition, an executive function that inhibits prepotent response tendency. The brain activity and resting-state functional connectivity were measured to analyze a parcellation-based network that was aimed at identifying a candidate PPC region essential for response inhibition in humans. The intraparietal sulcus (IPS) was activated during response inhibition and connected with the inferior frontal cortex and the presupplementary motor area, the two frontal regions known to be necessary for response inhibition. Next, transcranial mag

SUBMITTER: Osada T 

PROVIDER: S-EPMC6435821 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature