Connectivity differences between consciousness and unconsciousness in non-rapid eye movement sleep: a TMS-EEG study.

ABSTRACT: The neuronal connectivity patterns that differentiate consciousness from unconsciousness remain unclear. Previous studies have demonstrated that effective connectivity, as assessed by transcranial magnetic stimulation combined with electroencephalography (TMS-EEG), breaks down during the loss of consciousness. This study investigated changes in EEG connectivity associated with consciousness during non-rapid eye movement (NREM) sleep following parietal TMS. Compared with unconsciousness, conscious experiences during NREM sleep were associated with reduced phase-locking at low frequencies (<4 Hz). Transitivity and clustering coefficient in the delta and theta bands were also significantly lower during consciousness compared to unconsciousness, with differences in the clustering coefficient o

SUBMITTER: Lee M 

PROVIDER: S-EPMC6435892 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature