Identification of glucosyl transferase inhibitors from Psidium guajava against Streptococcus mutans in dental caries.

ABSTRACT: Dental caries is a multi factorial disease that starts with microbiological shifts affected by salivary flow, composition, exposure to fluoride, consumption of dietary sugars, and preventive behaviours. The Streptococcus mutans (S. mutans) is an initiator of caries because there is a variety of a virulence factor unique to the bacterium that has been isolated and plays an important role in caries formation. The aim of the present study is to identify the beneficial effect of bioactive compounds in Psidium guajava (P. guajava) and its inhibitory role against S. mutans in dental caries. The methanolic extract was used for analysis of GC-MS for the identification of bioactive compounds. The results confirm the existence of 7 different compounds

SUBMITTER: Bhagavathy S 

PROVIDER: S-EPMC6435953 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature