The Effects of Storage Age of Blood in Massively Transfused Burn Patients: A Secondary Analysis of the Randomized Transfusion Requirement in Burn Care Evaluation Study.

ABSTRACT:

Objectives

Major trials examining storage age of blood transfused to critically ill patients administered relatively few blood transfusions. We sought to determine if the storage age of blood affects outcomes when very large amounts of blood are transfused.

Design

A secondary analysis of the multicenter randomized Transfusion Requirement in Burn Care Evaluation study which compared restrictive and liberal transfusion strategies.

Setting

Eighteen tertiary-care burn centers.

Patients

Transfusion Requirement in Burn Care Evaluation evaluated 345 adults with burns greater than or equal to 20% of the body surface area. We included only the 303 patients that received blood transfusions.

Interventions

The storage ages of all transfused red cell units were colle

SUBMITTER: Cartotto R 

PROVIDER: S-EPMC6436380 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature