Methods of conservative antibiotic treatment of acute uncomplicated appendicitis: A systematic review.

ABSTRACT:

Background

Meta-analyses and a recent guideline acknowledge that conservative management of uncomplicated appendicitis with antibiotics can be successful for patients who wish to avoid surgery. However, guidance as to specific management does not exist.

Methods

PUBMED and EMBASE search of trials describing methods of conservative treatment was conducted according to Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines.

Results

Thirty-four studies involving 2,944 antibiotic-treated participants were identified. The greatest experience with conservative treatment is in persons 5 to 50 years of age. In most trials, imaging was used to confirm localized appendicitis without evidence of abscess, phlegmon, or tumor. Antibiotics regimens were general

SUBMITTER: Talan DA 

PROVIDER: S-EPMC6437084 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature