Effects of aqueous suppressants and prostaglandin analogues on early wound healing after glaucoma implant surgery.

ABSTRACT: A hypertensive phase frequently develops in the early postoperative period after glaucoma shunt operations. Anti-glaucoma eye drop use is essential when postoperative intraocular pressure (IOP) is not controlled. We investigated whether the use of early topical anti-glaucoma medication affects wound healing following glaucoma tube surgery. Eyes were randomly assigned to receive topical aqueous suppressant (timolol-dorzolamide fixed combination), prostaglandin (PG) analogue (travoprost), or normal saline (control group). First, we observed the effects of topical eye drops on Tenon's tissue in non-operated eyes in rabbits. Second, we examined the effects of these eye drops on rabbit eyes that underwent Ahmed glaucoma drainage device implantation, including the effects on the histopathologica

SUBMITTER: Jung KI 

PROVIDER: S-EPMC6437192 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature