Seminal plasma modulates expression of endometrial inflammatory meditators in the bovine†.

ABSTRACT: Seminal plasma has conventionally been viewed as a transport and survival medium for mammalian sperm; however, its role now extends beyond this process to actively targeting female tissues. Studies in rodents, swine, and humans demonstrate that seminal plasma induces molecular and cellular changes within the endometrium or cervix following insemination. Seminal-plasma-induced alterations to the maternal environment have been theorized to facilitate embryo development, modulate maternal immunity toward the conceptus, and potentially improve pregnancy success. It is unknown if bovine seminal plasma modulates the uterine environment following insemination in the cow, where routine use of artificial insemination reduces maternal exposure to seminal plasma. We hypothesize that seminal plasma mo

SUBMITTER: Ibrahim LA 

PROVIDER: S-EPMC6437260 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature