A nationwide survey on non-B, non-C hepatocellular carcinoma in Japan: 2011-2015 update.

ABSTRACT:

Background

We previously reported that the incidence of hepatocellular carcinoma (HCC) with non-viral etiologies increased rapidly between 1991 and 2010 in Japan.

Methods

To update this investigation, we enrolled patients who were initially diagnosed as having non-B, non-C HCC at participating hospitals between 2011 and 2015. In addition to the patient characteristics investigated in the previous report, we also investigated the duration of alcohol consumption. The overall survival rate was analyzed using the Kaplan-Meier method, and the hazard function against the body mass index (BMI) was plotted using cubic splines.

Results

A total of 2087 patients were enrolled. The proportion of patients with non-viral etiologies has continued to increase from 10.0% in 1991 to 32

SUBMITTER: Tateishi R 

PROVIDER: S-EPMC6437291 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature