Effects of airway obstruction and hyperinflation on electrocardiographic axes in COPD.

ABSTRACT:

Background

COPD influences cardiac function and morphology. Changes of the electrical heart axes have been largely attributed to a supposed increased right heart load in the past, whereas a potential involvement of the left heart has not been sufficiently addressed. It is not known to which extent these alterations are due to changes in lung function parameters. We therefore quantified the relationship between airway obstruction, lung hyperinflation, several echo- and electrocardiographic parameters on the orientation of the electrocardiographic (ECG) P, QRS and T wave axis in COPD.

Methods

Data from the COPD cohort COSYCONET were analyzed, using forced expiratory volume in 1 s (FEV₁), functional residual capacity (FRC), left ventricular (LV) mass, and ECG data.

SUBMITTER: Alter P 

PROVIDER: S-EPMC6437876 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature