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Brivaracetam add-on therapy for drug-resistant epilepsy.


ABSTRACT:

SUBMITTER: Bresnahan R 

PROVIDER: S-EPMC6437881 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature

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Brivaracetam add-on therapy for drug-resistant epilepsy.

Bresnahan Rebecca R   Panebianco Mariangela M   Marson Anthony G AG  

The Cochrane database of systematic reviews 20190328


<h4>Background</h4>Epilepsy is one of the most common neurological disorders. It is estimated that up to 30% of patients with epilepsy continue to have epileptic seizures despite treatment with an antiepileptic drug. These patients are classified as drug-resistant and require treatment with a combination of multiple antiepileptic drugs. Brivaracetam is a third-generation antiepileptic drug that is a high-affinity ligand for synaptic vesicle protein 2A. This review investigates the use of brivara  ...[more]

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